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Home > Areas of Focus > Science of Biodefense
Science of Biodefense
  

Analysis of new developments in the biological sciences that will affect the trajectory of biological weapons threats and the development of countermeasures, as well as recommendations on scientific applications and actions the scientific community could take to reduce the threat of biological weapons. 

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Center Publications and Original Articles

Publications on Science and Biosecurity

Articles written by Center staff relating to scientific research and governance.

  1. Meeting Report: Prevention of Biothreats: A Look Ahead

    Gronvall G, Bouri N, Rambhia K, Franco C, Watson M. Biosecurity and Bioterrorism. 2009;7(4).
    Tue, 22 Dec 2009 17:37:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2009/2009-12-22-prevent_biothreats.html

  2. Strategic Priorities for U.S. Biosecurity

    O'Toole T, Inglesby TV. Biosecurity and Bioterrorism. 2009;7(1).
    Mon, 30 Mar 2009 15:26:47 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2009/biomemo/2009-03-27-strategic_priorities_biosecurity.html

  3. Improving the Select Agent Program

    Gronvall GK. Bulletin of Atomic Scientists. 29 October 2008.
    Tue, 25 Nov 2008 16:46:52 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2008/2008-10-29-imprvselectagentprog.html

  4. Roundtable On-line Discussion: Is the Availability of Genetic Information Dangerous?

    Gronvall GK, Kuhn J, Hunger I, Ryabikhin LF. Bulletin of Atomic Scientists. 8 November 2007 to 28 February 2008.
    Fri, 18 Jul 2008 18:49:18 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2008/2008-02-28-isavailabilitygeneticinfodanger.html

  5. Immune-Boosting Adjuvants

    Chamberlain A, Gronvall GK. Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science. 2007;5(3):202-205. doi:10.1089/bsp.2007.0033.
    Sat, 01 Sep 2007 20:42:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2007_orig-articles/2007-09-01-immuneboostingadjuvants.html

  6. The Science of Biodefense: RNAi

    Chamberlain A, Gronvall GK. Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science. 2007;5(2):104-106. doi:10.1089/bsp.2007.0018.
    Fri, 01 Jun 2007 20:42:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2007_orig-articles/2007-06-01-rnai.html

  7. Meeting Report: High-Containment Biodefense Research Laboratories: Meeting Report and Center Recommendations

    Gronvall GK, Fitzgerald J, Chamberlain A, Inglesby TV, O'Toole T. Biosecurity and Bioterrorism. 2007;5(1).
    Wed, 04 Apr 2007 19:35:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2007_orig-articles/2007-04-04-highcontainmentbioresearchlab.html

  8. Billions for Biodefense: Federal Agency Biodefense Funding, FY2006-FY2007

    Lam C, Franco C, Schuler A. Biosecurity and Bioterrorism. 2006;4(2).
    Thu, 15 Jun 2006 15:46:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2006_orig-articles/2006-06-15-billionsforbiodefense2006-2007.html

  9. The Scientific Response to a Pandemic

    Gronvall GK, Waldhorn RE, Henderson DA. PLoS Pathogens. 2006;2(2) e9.
    Fri, 24 Feb 2006 15:14:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2006_orig-articles/2006-02-24-scientificresponsetoapandemic.html

  10. A New Role for Scientists in the Biological Weapons Convention

    Gronvall, GK. Nature Biotechnology. 2005; 23(10):1213-6.
    Sat, 15 Oct 2005 15:37:00 GMThttp://www.upmc-biosecurity.org/website/resources/publications/2005_orig-articles/2005-10-15-newroleforscientistsinbwc.html

   
 
Center Commentary

commentary_science

Commentary by Center staff regarding science and biosecurity.

  1. U.S. Biosecurity and the Center for Biosecurity's Work -- A Series of Interviews from Homeland Security: Inside and Out (03-17-2009)

    On March 17, 2009, for their radio show, Homeland Security Inside and Out, co-hosts Col. Randy Larsen and Dave McIntyre interviewed senior staff of the Center for a series of discussions about U.S. biosecurity strategy and related issues.
    Tue, 17 Mar 2009 17:39:00 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2009-03-17-inside_and_out/index.html

  2. Letter of Support to Senate for Reintroduction of Select Agent Reauthorization Act (03-03-2009)

    A letter of support to the Senate endorsing The Select Agent Program and Biosafety Improvement Act of 2009 (S.485 and H.R. 1225), an important piece of legislation to ensure that biodefense research can proceed securely.
    Wed, 04 Mar 2009 16:40:26 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2009-03-03-ltr_reintro_select_agent_senate.html

  3. Letter of Support to House for Reintroduction of Select Agent Reauthorization Act (03-03-2009)

    A letter of support to the House endorsing The Select Agent Program and Biosafety Improvement Act of 2009 (S.485 and H.R. 1225), an important piece of legislation to ensure that biodefense research can proceed securely.
    Wed, 04 Mar 2009 16:39:43 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2009-03-03-ltr_reintro_select_agent_house.html

  4. Written Testimony to House Armed Services Committee Hearing (01-22-2009)

    The Center submitted written testimony to the House Armed Services Committee January 22, 2009 hearing on "Preventing Weapons of Mass Destruction Proliferation and Terrorism."
    Thu, 22 Jan 2009 22:12:00 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2009-01-21-ltr_to_ike_skelton_john_mchugh.html

  5. Preventing and Deterring Biological Attacks: Priorities that Should Emerge From the WMD Commission Report (12-19-2008)

    The Center for Biosecurity strongly agrees with the Weapons of Mass Destruction (WMD) Commission report "World at Risk" that the threat of bioterrorism is urgent, growing, and requires decisive action.
    Fri, 19 Dec 2008 21:42:52 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2008-12-19-preventdeterbioweapons.html

  6. Letter of Support for H.R. 6671 Biosafety Act (08-13-2008)

    The Center for Biosecurity of UPMC has endorsed the Select Agent Program and Biosafety Improvement Act of 2008 (h.r. 6671).
    Thu, 14 Aug 2008 16:45:47 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2008-08-13-ltr_support_hr6671_biosafety.html

  7. Letter of Support for Burr-Kennedy Biosafety Act (06-17-2008)

    The Center for Biosecurity of UPMC has endorsed the Select Agent Program and Biosafety Improvement Act of 2008 (s. 3217), introduced by Senators Burr and Kennedy on June 12, 2008.
    Tue, 17 Jun 2008 21:50:00 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2008-06-17-ltr_support_biosafety_BurrKennedy.html

  8. Ten Notable Publications of 2007 (01-08-2008)

    Center for Biosecurity's picks for 10 notable publications of 2007.
    Wed, 09 Jan 2008 00:15:00 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2008-01-08-notablepubs2007.html

  9. Prepared Statement: 6th Review Conference of the Biological Weapons Convention (11-21-2006)

    Prepared statement delivered by Dr. Gigi Kwik Gronvall before the Biological Weapons Convention
    Tue, 21 Nov 2006 21:50:00 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2006-11-21-bwc_statement


 
Congressional Testimony and Briefings

Testimony on Science and Biosecurity

Congressional testimony by Center staff regarding scientific research.

  1. Written Testimony to House Armed Services Committee Hearing (01-22-2009)

    The Center submitted written testimony to the House Armed Services Committee January 22, 2009 hearing on "Preventing Weapons of Mass Destruction Proliferation and Terrorism."
    Fri, 23 Jan 2009 22:12:27 GMThttp://www.upmc-biosecurity.org/website/resources/commentary/2009-01-21-ltr_to_ike_skelton_john_mchugh.html

  2. Hearing on Germs, Viruses, and Secrets: The Silent Proliferation of Bio-Laboratories in the U.S. (10-04-2007)

    Testimony of Gigi Kwik Gronvall before U.S. House of Representatives Committee on Energy and Commerce Subcommittee on Oversight and Investigations.
    Wed, 12 Dec 2007 20:02:06 GMThttp://www.upmc-biosecurity.org/website/resources/hearings/2007/20071004-germsvirusesandsecrets.html

  3. Department of Health and Human Services Budget Priorities for FY 2003 (02-28-2002)

    Testimony of Dr. Tara O'Toole before the Committee on the Budget, U.S. House of Representatives
    Thu, 28 Feb 2002 14:23:00 GMThttp://www.upmc-biosecurity.org/website/resources/hearings/2002/20020228FY2003budgetpriorities.html

  4. Hearing on the Threat of Bioterrorism and the Spread of Infectious Diseases (09-05-2001)

    Testimony of Dr. D.A. Henderson before the Committee on Foreign Relations, U.S. Senate
    Wed, 05 Sep 2001 15:00:00 GMThttp://www.upmc-biosecurity.org/website/resources/hearings/2001/20010905btandspreadofid.html

  5. Bioterrorism: Our Frontline Response--Evaluating U.S. Public Health and Medical Readiness (03-25-1999)

    Testimony of Dr. D.A. Henderson before the Subcommittee on Public Health, Committee on Health, Education, Labor and Pensions, U.S. Senate
    Thu, 25 Mar 1999 18:20:00 GMThttp://www.upmc-biosecurity.org/website/resources/hearings/1999/19990325usphandmedreadiness.html

  
 
Center Events and Scenarios

International Conference on Biosafety and Biorisks.
Lyon, France. March 2–3, 2005.

  
Multimedia

The World at Risk Report and Laboratory Security. Dr. Gigi Kwik Gronvall interviewed March 17, 2009, for Federal News Radio’s Homeland Security: Inside and Out. Listen to interview

The Challenge of Bioterrorism, Present and Future: Keynote address delivered by Dr. Tara O’Toole in November 2008 at the Commissioned Training of Major Infectious Disease Emergencies and Bioterrorism Preparedness at Princess Margaret’s Hospital in Hong Kong. Watch the video | View the slides | View other lectures from this conference

 
U.S. Government Documents

U.S. government documents and reports related to science and biosecurity

U.S. government documents - all topic areas

Biosecurity-related federal legislation


See Also

Clinicians' Biosecurity Network Report Archive: Science and Biosecurity

Bioterrorism: Redefining Prevention. Graham B, Talent J. Biosecurity and Bioterrorism. 2009;7(2).

Casting a Wider Net for Countermeasure R&D Funding Decisions. Klotz L. Biosecurity and Bioterrorism. 2007;5(4).

Security is More than Public Health: Commentary on ‘Casting a Wider Net for Countermeasure R&D Funding Decisions’. Epstein GL. Biosecurity and Bioterrorism. 2007;5(4).

National Science Advisory Board for Biosecurity (NSABB) meetings.

The Dual-Use Dilemma for the Life Sciences: Perspectives, Conundrums, and Global Solutions. Atlas RM, Dando M. Biosecurity and Bioterrorism. 2006;4(3).

Interview with Mark Klempner, MD, Principal Investigator, National Emerging Infectious Diseases Laboratories, and Associate Provost for Research, Boston University School of Medicine. Drexler M. Biosecurity and Bioterrorism. 2006;4(2)

Billions for Biodefense: Federal Agency Biodefense Funding, FY2006-FY2007. Lam C, Franco C, Schuler A. Biosecurity and Bioterrorism. 2006;4(2).

Regulating Biorisks: Developing a Coherent Policy Logic (Part 1). Corneliussen F. Biosecurity and Bioterrorism. 2006;4(2).

Regulating Biorisks: Developing A Coherent Policy Logic (Part II). Lentzos F. Biosecurity and Bioterrorism. 2007, 5(1).

Biological Threat Characterization Research: A Critical Component of National Biodefense. Petro JB, Carus WS. Biosecurity and Bioterrorism. 2005;3(4).

Avoiding the Biological Security Dilemma: A Response to Petro and Carus. Tucker JB. Biosecurity and Bioterrorism. 2006;4(2).

Avoiding the Biological Security Dilemma at Our Own Peril: A Response to Tucker. Petro JB, Carus WS. Biosecurity and Bioterrorism. 2006;4(2).

Biotechnology Research in an Age of Terrorism. Committee on Research Standards and Practices to Prevent the Destructive Application of Biotechnology, National Research Council, National Academy of Sciences. Washington, DC: The National Academies Press; 2004.

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